Recombinant Human OSMR/IL31RB Protein (aa 28-739, His Tag) | PKSH032836

Recombinant Human OSMR/IL31RB Protein (aa 28-739, His Tag) | PKSH032836 | Gentaur US, UK & Europe Disrtribition

Synonyms: Oncostatin-M-Specific Receptor Subunit Beta; Interleukin-31 Receptor Subunit Beta; IL-31 Receptor Subunit Beta; IL-31R Subunit Beta; IL-31R-Beta; IL-31RB; OSMR;OSMRB;PLCA1

Active Protein: N/A

Activity: Recombinant Human Oncostatin-M-Specific Receptor Subunit beta is produced by our Mammalian expression system and the target gene encoding Glu28-Ser739 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Oncostatin-M-Specific Receptor Subunit beta is produced by our Mammalian expression system and the target gene encoding Glu28-Ser739 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 82.0 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Oncostatin-M-Specific Receptor Subunit β (OSMRβ) is a 150 - 180 kDa member of the IL-6 receptor family. OSMRβ associates with gp130 to form the type II OSM receptor, the receptor is responsive to OSM. Gp130 subunit is shared by other IL-6 family cytokine receptors, and OSMRβ associates with gp130-like receptor (GPL) to form a receptor complex responsive to IL-31. The human OSMRβ cDNA encodes a 979 amino acid (aa) precursor, the precursor includes a 27 aa signal sequence, a 712 aa extracellular domain (ECD), a 22 aatransmembrane segment, and a 218 aa cytoplasmic domain. The ECD contains one partial and one complete hematopoietin domain, an Ig-like domain, and three Fibronectin type-III domains.

Research Area: Signal Transduction, epigenetics and nuclear signal, immunology,