Description
Recombinant Human NUDT5/ADP-sugar Pyrophosphatase Protein (His Tag) | PKSH030745 | Gentaur US, UK & Europe Disrtribition
Synonyms: hYSAH1;YSA1;YSA1H;YSAH1
Active Protein: N/A
Activity: A DNA sequence encoding the human NUDT5 (Q9UKK9) (Glu2-Phe219) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human NUDT5 (Q9UKK9) (Glu2-Phe219) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 26.3 kDa
Formulation: Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0
Reconstitution: Please refer to the printed manual for detailed information.
Background: ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites. NUDT5 functions as a MutT-related protein and catalyzes the hydrolysis of 8-oxoGDP to 8-oxoGMP, thereby preventing misincorporation of 8-oxoGua into RNA. NUDT5 may play significant roles in regulating the G1-S transition in mammalian cells. It can also hydrolyze other nucleotide sugars with low activity.
Research Area: Signal Transduction, epigenetics and nuclear signal, metabolism,
