Description
Recombinant Human NUDT2/Ap4A hydrolase Protein (His Tag) | PKSH030819 | Gentaur US, UK & Europe Disrtribition
Synonyms: APAH1
Active Protein: N/A
Activity: A DNA sequence encoding the human NUDT2 (P50583) (Met 1-Ala 147) was expressed, with a polyhistide tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human NUDT2 (P50583) (Met 1-Ala 147) was expressed, with a polyhistide tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 97 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 18.3 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: This gene encodes a member of the MutT family of nucleotide pyrophosphatases, a subset of the larger NUDIX hydrolase family. The gene product possesses a modification of the MutT sequence motif found in certain nucleotide pyrophosphatases. The enzyme asymmetrically hydrolyzes Ap4A to yield AMP and ATP and is responsible for maintaining the intracellular level of the dinucleotide Ap4A, the function of which has yet to be established. This gene may be a candidate tumor suppressor gene. Alternative splicing has been observed at this locus and four transcript variants, all encoding the same protein, have been identified.
Research Area: epigenetics and nuclear signal
