Description
Recombinant Human NRCAM Protein (Fc Tag) | PKSH033581 | Gentaur US, UK & Europe Disrtribition
Synonyms: Neuronal cell adhesion molecule; Nr-CAM; Neuronal surface protein Bravo; hBravo; gCAM-related cell adhesion molecule; Ng-CAM-related; KIAA0343; gCAM-related cell adhesion molecule
Active Protein: N/A
Activity: Recombinant Human NRCAM is produced by our Mammalian expression system and the target gene encoding Gln25-Asn600(Pro526Ala) is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Human NRCAM is produced by our Mammalian expression system and the target gene encoding Gln25-Asn600(Pro526Ala) is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 91.2 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Neuronal cell adhesion molecule(NRCAM) is a single-pass type I membrane protein, containing 5 fibronectin type-III domains and 6 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. NrCAM is engaged in such biological processes as axonal fasciculation, cell-cell adhesion, central nervous system development, clustering of voltage-gated sodium channels, neuron migration, positive regulation of neuron differentiation, regulation of axon extension, and synaptogenesis. It also may play a role in the molecular assembly of the nodes of Ranvier. NrCAM effects are also linked with different recognition processes and signal transduction pathways regulating cell differentiation, proliferation, or migration.
Research Area: N/A
