Description
Recombinant Human NHP2/NOLA2 Protein (His Tag) | PKSH032829 | Gentaur US, UK & Europe Disrtribition
Synonyms: H/ACA ribonucleoprotein complex subunit 2; Nucleolar protein family A member 2; snoRNP protein NHP2; NHP2; NOLA2; NHP2P.
Active Protein: N/A
Activity: Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human Nucleolar protein family A member 2 is produced by our E.coli expression system and the target gene encoding Met1-Leu153 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 19.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 100mM NaCl, 1mM DTT, pH 8.0.
Reconstitution: Not Applicable
Background: NHP2 belongs to the H/ACA snoRNPs gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been organized into 2 families: C/D and H/ACA. NHP2 forms a small ribonucleoprotein particle with GAR1 (NOLA1). NHP2 is involved in a variety of aspects of rRNA processing and modification. NHP2 localizes to the dense fibrillar component of the nucleolus and in nuclear Cajal bodies. NHP2 may also be required for correct processing or intranuclear trafficking of TERC, the RNA component of the telomerase reverse transcriptase (TERT) holoenzyme.
Research Area: epigenetics and nuclear signal
