Description
Recombinant Human Neurotensin Protein (Fc Tag) | PKSH030549 | Gentaur US, UK & Europe Disrtribition
Synonyms: NMN-125;NN;NT;NT/N;NTS1
Active Protein: N/A
Activity: A DNA sequence encoding the human NTS (NP_006174.1) (Met1-Leu148) was expressed with the Fc region of human IgG1 at the C-terminus.
Protein Construction: A DNA sequence encoding the human NTS (NP_006174.1) (Met1-Leu148) was expressed with the Fc region of human IgG1 at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: HEK293 Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 41 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4
Reconstitution: Please refer to the printed manual for detailed information.
Background: DPEP2 (MBD-2) belongs to the membrane-bound dipeptidase family. There are three members of this family as membrane-bound dipeptidase-1 (MBD-1), membrane-bound dipeptidase-2 (MBD-2) and membrane-bound dipeptidase-3 (MBD-3).MBD-2 is expressed at highest levels in lung, heart, and testis and at some what lower levels in spleen.MBD-2 is membrane-bound through a glycosylphosphatidyl-inositol linkage and probably is a metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4).It is generally recognized that rapid cleavage of LTD4 is important in inactivating the broncho-and vaso-constrictive effects of cysteinyl LTs in asthmatic and inflammatory processes.
Research Area: Signal Transduction, Neuroscience, metabolism,
