Recombinant Human NCAM1 Protein (His Tag) | PKSH032793

Recombinant Human NCAM1 Protein (His Tag) | PKSH032793 | Gentaur US, UK & Europe Disrtribition

Synonyms: CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM

Active Protein: N/A

Activity: Recombinant Human Neural cell adhesion molecule 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro603 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Neural cell adhesion molecule 1 is produced by our Mammalian expression system and the target gene encoding Leu20-Pro603 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 65.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Neural cell adhesion molecule 1 (NCAM-1) is a single-pass type I membrane protein, it belongs to a family of membrane-bound glycoproteins that are involved in Ca2+ independent cell matrix and homophilic or heterophilic cell-cell interactions. NCAM-1 is synthesized as a 761 aa preproprecursor that contains a 19 aa signal sequence, a 722 aa GPI-linked mature region, and a 20 aa C-terminal prosegment. The molecule contains five C-2 type Ig-like domains and two fibronectin type-III domains. NCAM-1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Acting as a receptor for rabies virus, NCAM-1 in the adult brain shows a decline of sialylation relative to earlier developmental periods.

Research Area: N/A