Recombinant Human NCAM1 Protein (ECD, His Tag) | PKSH031994

Recombinant Human NCAM1 Protein (ECD, His Tag) | PKSH031994 | Gentaur US, UK & Europe Disrtribition

Synonyms: CD56; NCAM-1; CD56 antigen; MSK39; N-CAM-1; NCAM-1; neural cell adhesion molecule 1; neural cell adhesion molecule; NCAM

Active Protein: N/A

Activity: A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met1-Pro603) was expressed with a polyhistidine tag at the C-terminus.

Protein Construction: A DNA sequence encoding the human NCAM1 (NP_001070150.1) (Met1-Pro603) was expressed with a polyhistidine tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 66.1 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4. 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. 2. Please contact us for any concerns or special

Reconstitution: Please refer to the printed manual for detailed information.

Background: NCAM1, also known as CD56, is a neural adhesion protein (NCAM) which belongs to the immunoglobulin superfamily. NCAM is involved in neural development and in plasticity in the adult brain. UCHL1 is a novel interaction partner of both NCAM isoforms that regulates their ubiquitination and intracellular trafficking. NCAM1 is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. NCAM1 has also been shown to be involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance.

Research Area: Signal Transduction, Neuroscience, Stem cells