Recombinant Human MR-ProADM protein(His tag) | PKSH500076

Recombinant Human MR-ProADM protein(His tag) | PKSH500076 | Gentaur US, UK & Europe Disrtribition

Synonyms: AM;ProAM N-terminal 20 peptide;PAMP;ProAM-N20

Active Protein: N/A

Activity: A DNA sequence encoding theHuman MR-ProADM protein (P35318) (Glu45-Val92) was expressed with a N-GST.

Protein Construction: A DNA sequence encoding theHuman MR-ProADM protein (P35318) (Glu45-Val92) was expressed with a N-GST.

Fusion Tag: N-GST

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 31.3 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: AM and PAMP are potent hypotensive and vasodilatator agents. Numerous actions have been reported most related to the physiologic control of fluid and electrolyte homeostasis. In the kidney, am is diuretic and natriuretic, and both am and pamp inhibit aldosterone secretion by direct adrenal actions. In pituitary gland, both peptides at physiologically relevant doses inhibit basal ACTH secretion. Both peptides appear to act in brain and pituitary gland to facilitate the loss of plasma volume, actions which complement their hypotensive effects in blood vessels.

Research Area: N/A