Description
Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Fc Tag)(Active) | PKSH031985 | Gentaur US, UK & Europe Disrtribition
Synonyms: BDA2;BDA2A;BMP-2;BMP2A;BMP2
Active Protein: Active protein
Activity: A DNA sequence encoding the mature form of human BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of human IgG1 at the C-terminus. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Protein Construction: A DNA sequence encoding the mature form of human BMP2 (NP_001191.1) (Gln 283-Arg 396) was fused with the Fc region of human IgG1 at the C-terminus. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.
Fusion Tag: C-Fc
Species: Human
Expressed Host: HEK293 Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 39.5 kDa
Formulation: Lyophilized from sterile 100mM Glycine, 10mM NaCl, 50mM Tris, pH 7.5 1. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Specific concentrations are included in the hardcopy of COA. 2. Please contact
Reconstitution: Please refer to the printed manual for detailed information.
Background: BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.
Research Area: Signal Transduction, Cardiovascular, Cancer, Stem cells
