Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Active) | PKSH031986

Recombinant Human/Mouse/Rat/Rhesus/Canine BMP-2 Protein (Active) | PKSH031986 | Gentaur US, UK & Europe Disrtribition

Synonyms: BDA2;BDA2A;BMP-2;BMP2A;BMP2

Active Protein: Active protein

Activity: A DNA sequence encoding the mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.

Protein Construction: A DNA sequence encoding the mature form of human BMP2 (NP_001191.1) (Gln283-Arg396) was expressed. The mature form sequences of human, mouse, rat, rhesus and canine BMP2 are identical.

Fusion Tag:

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 13 kDa

Formulation: Lyophilized from sterile 30 % CAN, 0.1 % TFA, pH 2.9.

Reconstitution: Please refer to the printed manual for detailed information.

Background: BMP-2 protein, like other bone morphogenetic proteins, plays an important role in the development of bone and cartilage. BMP-2 protein is involved in the hedgehog pathway, TGF beta signaling pathway, and cytokine-cytokine receptor interaction. BMP-2 and BMP-7 are osteogenic BMPs that have been demonstrated to potently induce osteoblast differentiation in a variety of cell types. BMP-2, BMP-4 and BMP-7 are known to be of major importance in bone formation and repair. In cancerous tissues BMP-2 protein may play an important role in the progression of glioma.

Research Area: Signal Transduction, Cardiovascular, Cancer, Stem cells