Recombinant Human MOG Protein (Human Cells, His Tag) | PKSH032769

Recombinant Human MOG Protein (Human Cells, His Tag) | PKSH032769 | Gentaur US, UK & Europe Disrtribition

Synonyms: Myelin-Oligodendrocyte Glycoprotein; MOG;BTN6;BTNL11;MOGIG2;NRCLP7

Active Protein: N/A

Activity: Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our Mammalian expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 15.3 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space which allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like disease in experimental animals;namely experimental autoimmune encephalomyelitis (EAE) in rodents and monkeys.

Research Area: Neuroscience