Description
Recombinant Human MOG Protein (E.coli, His Tag) | PKSH032768 | Gentaur US, UK & Europe Disrtribition
Synonyms: Myelin-Oligodendrocyte Glycoprotein; MOG;BTN6;BTNL11;MOGIG2;NRCLP7
Active Protein: N/A
Activity: Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Myelin Oligodendrocyte Glycoprotein is produced by our E.coli expression system and the target gene encoding Gly30-Gly154 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 15.2 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM HAc-NaAc, 150mM NaCl, pH 4.5.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Myelin Oligodendrocyte Glycoprotein (MOG) is a transmembrane protein; which is expressed exclusively in the CNS. MOG contains a single Ig-domain exposed to the extracellular space that allows autoantibodies easy access. MOG protein has been identified as a crucial autoantigen for multiple sclerosis in humans. MOG is capable to produce a demyelinating multiple sclerosis-like diseases in experimental animals; namely experimental autoimmune encephalomyelitis (EAE); in rodents and monkeys.
Research Area: Neuroscience
