Description
Recombinant Human MMP-9 Protein (His Tag) | PKSH033431 | Gentaur US, UK & Europe Disrtribition
Synonyms: Matrix metalloproteinase-9;92 kDa gelatinase;92 kDa type IV collagenase;Gelatinase B;MMP9;CLG4B;GELB;MANDP2
Active Protein: N/A
Activity: Recombinant Human Matrix metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Matrix metalloproteinase-9 is produced by our Mammalian expression system and the target gene encoding Ala19-Asp707 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 77.4 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 2mM CaCl2, 150mM NaCl, 0.05% Brij35(w/v), pH 7.5.
Reconstitution: Not Applicable
Background: Matrix metallopeptidase 9 (MMP-9) is an enzyme encoded by the MMP9 gene. This protein; which is produced by normal alveolar macrophages and granulocytes; can be activated by 4-aminophenylmercuric acetate and phorbol ester and up-regulated by ARHGEF4; SPATA13 and APC via the JNK signaling pathway in colorectal tumor cells. MMP-9 is involved in the breakdown of extracellular matrix in normal physiological processes; such as embryonic development; reproduction; angiogenesis; bone development; wound healing; cell migration; learning and memory; as well as in pathological processes; such as arthritis; intracerebral hemorrhage; and metastasis.
Research Area: Signal Transduction, Cell biology, Cardiovascular, Cancer,
