Description
Recombinant Human MGAT2/GlcNAc-TII Protein (His Tag) | PKSH032737 | Gentaur US, UK & Europe Disrtribition
Synonyms: Alpha-1;6-Mannosyl-Glycoprotein 2-Beta-N-Acetylglucosaminyltransferase; Beta-1;2-N-acetylglucosaminyltransferase II; GlcNAc-T II; NT-II; Mannoside Acetylglucosaminyltransferase 2; N-Glycosyl-Oligosaccharide-Glycoprotein N-Acetylglucosaminyltransferase II; MGAT2
Active Protein: N/A
Activity: Recombinant Human Mannoside Acetylglucosaminyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Arg30-Gln447 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Mannoside Acetylglucosaminyltransferase 2 is produced by our Mammalian expression system and the target gene encoding Arg30-Gln447 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 49.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH8.0 .
Reconstitution: Not Applicable
Background: Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A.
Research Area: Tags & Cell Markers
