Recombinant Human MeCP2 protein(His tag) | PKSH500104

Recombinant Human MeCP2 protein(His tag) | PKSH500104 | Gentaur US, UK & Europe Disrtribition

Synonyms: MeCp-2 protein

Active Protein: N/A

Activity: A DNA sequence encoding theHuman MeCP2 protein (P51608) (Met1-Lys177) was expressed with a N-His .

Protein Construction: A DNA sequence encoding theHuman MeCP2 protein (P51608) (Met1-Lys177) was expressed with a N-His .

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 19 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5, 5% trehalose, 5% mannitol, 0.01% tween-80.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).

Research Area: N/A