Recombinant Human MECP2 Protein (His Tag) | PKSH032751

Recombinant Human MECP2 Protein (His Tag) | PKSH032751 | Gentaur US, UK & Europe Disrtribition

Synonyms: Methyl-CpG-binding protein 2;MECP2;MeCp-2 protein

Active Protein: N/A

Activity: Recombinant Human Methyl-CpG-binding protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Ser486 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Methyl-CpG-binding protein 2 is produced by our Mammalian expression system and the target gene encoding Met1-Ser486 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 90 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 53.5 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM Tris, 150mM NaCl, pH 8.0.

Reconstitution: Please refer to the printed manual for detailed information.

Background: The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is particularly abundant in brain cells.In the brain, the MeCP2 protein likely plays a role in maintaining connections (synapses) between neurons, where cell-to-cell communication occurs. The alternative splicing of proteins is critical for normal communication between neurons and may also be necessary for the function of other types of brain cells.

Research Area: Neuroscience, epigenetics and nuclear signal