Recombinant Human MAP1D Protein (His Tag) | PKSH032749

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SKU:
575-PKSH032749
€676.00
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Description

Recombinant Human MAP1D Protein (His Tag) | PKSH032749 | Gentaur US, UK & Europe Disrtribition

Synonyms: Methionine Aminopeptidase 1D Mitochondrial; Methionyl Aminopeptidase Type 1D Mitochondrial; METAP1D; MAP1D;MAP 1D;MetAP 1D;Metap1l

Active Protein: N/A

Activity: Recombinant Human Methionine Aminopeptidase 1D Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg44-Ala335 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.

Protein Construction: Recombinant Human Methionine Aminopeptidase 1D Mitochondrial is produced by our E.coli expression system and the target gene encoding Arg44-Ala335 is expressed with a 6His tag at the N-terminus, 6His tag at the C-terminus.

Fusion Tag: N, C-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 35.4 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, pH 8.0.

Reconstitution: Not Applicable

Background: Methionine Aminopeptidase 1D (METAP1D) is a mitochondrion protein that belongs to the peptidase M24A family. METAP1D is overexpressed at the protein level in colon cancer cell lines and colon tumors as compared to normal tissues. N-terminal methionine removal is an important cellular process required for proper biological activity, subcellular localization, and eventual degradation of many proteins. METAP1D is also active with zinc, manganese or divalent ions. It may also play an important role in colon tumorigenesis.

Research Area: Signal Transduction, epigenetics and nuclear signal,

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