Description
Recombinant Human LTA4H Protein (His Tag) | PKSH032704 | Gentaur US, UK & Europe Disrtribition
Synonyms: Leukotriene A-4 hydrolase;LTA-4 hydrolase;Leukotriene A(4) hydrolase; LTA4;LTA4H
Active Protein: N/A
Activity: Recombinant Human Leukotriene A-4 hydrolase is produced by our Mammalian expression system and the target gene encoding Met1-Asp611 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Leukotriene A-4 hydrolase is produced by our Mammalian expression system and the target gene encoding Met1-Asp611 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 70.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM MES, 2mM EDTA, 20%Glycerol, pH5.0.
Reconstitution: Not Applicable
Background: LTA4H, which is short for Leukotriene A-4 hydrolase, is a 611 aa. protein. It belongs to the peptidase M1 family, and exists in cytoplasm. This protein has at least 4 isforms produced by alternative splicing, and two of them are expressed in monocytes, lymphocytes, neutrophils, reticulocytes, platelets and fibroblasts. LTA4H involves in lipid metabolism and leukotriene B4 biosynthesis. It is a epoxide hydrolase that catalyzes the final step in the biosynthesis of the proinflammatory mediator leukotriene B4. It also has aminopeptidase activity
Research Area: Cancer, immunology, metabolism
