Recombinant Human LSAMP Protein (Fc Tag)(Active) | PKSH030896

Recombinant Human LSAMP Protein (Fc Tag)(Active) | PKSH030896 | Gentaur US, UK & Europe Disrtribition

Synonyms: FLJ34254;FLJ35396;FLJ37216;FLJ54658;IGLON3;LAMP

Active Protein: Active protein

Activity: A DNA sequence encoding the human LSAMP (Q13449) (Met 1-Asn 315); without the pro peptide; was was fused with the Fc region of human IgG1 at the C-terminus.

Protein Construction: A DNA sequence encoding the human LSAMP (Q13449) (Met 1-Asn 315); without the pro peptide; was was fused with the Fc region of human IgG1 at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: HEK293 Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 59 kDa

Formulation: Lyophilized from sterile PBS, pH 7.4

Reconstitution: Please refer to the printed manual for detailed information.

Background: The limbic system-associated membrane protein (LAMP) is a cell surface glycoprotein expressed by cortical and subcortical regions of the mammalian CNS that comprise or receive direct projections from limbic system structures. The 64-68-kDa glycoprotein limbic system-associated membrane protein (LsAMP) is expressed on the surface of somata and proximal dendrites of neurons. These areas perform cognitive and autonomic functions; also learning and memory. The functional analysis indicates that LsAMP acts as a selective adhesion molecule; serving as a guidance cue for specific patterns of connectivity; which underlies the normal development of the limbic system. In animal studies there have been found that rats with increased level of anxiety had 1.6-fold higher expression of LsAMP gene in the periaqueductal gray compared to rats with low level of anxiety; indicating a possible role of LsAMP in the regulation of anxiety.

Research Area: Neuroscience