Description
Recombinant Human LRP12 Protein (His Tag) | PKSH032710 | Gentaur US, UK & Europe Disrtribition
Synonyms: Low-Density Lipoprotein Receptor-Related Protein 12; LRP-12; Suppressor of Tumorigenicity 7 Protein; LRP12; ST7
Active Protein: N/A
Activity: Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12 is produced by our Mammalian expression system and the target gene encoding Asn28-Ile488 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Low-Density Lipoprotein Receptor-Related Protein 12 is produced by our Mammalian expression system and the target gene encoding Asn28-Ile488 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 52.5 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.2.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Low-Density Lipoprotein Receptor-Related Protein 12 (LRP12) belongs to the LDLR family. LRP12 is a type I transmembrane protein annd widely expressed in heart, skeletal muscle, brain, lung, placenta and pancreas. LRP12 contains 2 CUB domain and 5 LDL-receptor class A domain. LRP12 has been shown to interact with GNB2L1, ZFYVE9 and ITGB1BP3. LRP12 is a receptor probably, which may be involved in the internalization of lipophilic molecules and/or signal transduction. In addition, LRP12 may act as a tumor suppressor.
Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,
