Description
Recombinant Human LFA-3/CD58 Protein (His Tag) | PKSH033593 | Gentaur US, UK & Europe Disrtribition
Synonyms: Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; CD58; LFA3；Ag3; CD58 antigen
Active Protein: N/A
Activity: Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr） is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215(His147Tyr） is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 22.5 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes; erythrocytes; endothelial cells; epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells; antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition; the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.
Research Area: immunology
