Recombinant Human LFA-3/CD58 Protein (Fc Tag) | PKSH033594

Recombinant Human LFA-3/CD58 Protein (Fc Tag) | PKSH033594 | Gentaur US, UK & Europe Disrtribition

Synonyms: Lymphocyte Function-Associated Antigen 3; Surface Glycoprotein LFA-3; CD58; LFA3；Ag3; CD58 antigen

Active Protein: N/A

Activity: Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus.

Protein Construction: Recombinant Human CD58 is produced by our Mammalian expression system and the target gene encoding Phe29-Arg215 is expressed with a Fc tag at the C-terminus.

Fusion Tag: C-Fc

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 48.6 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4 .

Reconstitution: Please refer to the printed manual for detailed information.

Background: Lymphocyte function-associated antigen 3 (LFA-3/CD58) is a single-pass type I membrane protein. CD58 is widely expressed on hematopoietic and non-hematopoietic human tissue and has been found on leukocytes; erythrocytes; endothelial cells; epithelial cells and fibroblasts of human origin. It is a Ligand of the T-lymphocyte CD2 glycoprotein. This interaction is important in mediating thymocyte interactions with thymic epithelial cells; antigen-independent and -dependent interactions of T-lymphocytes with target cells and antigen-presenting cells and the T-lymphocyte rosetting with erythrocytes. In addition; the LFA-3/CD2 interaction may prime response by both the CD2+ and LFA-3+ cells.

Research Area: immunology