Description
Recombinant Human LBP Protein (His Tag) | PKSH033414 | Gentaur US, UK & Europe Disrtribition
Synonyms: Lipopolysaccharide-Binding Protein; LBP;BPIFD2
Active Protein: N/A
Activity: Recombinant Human Lipopolysaccharide-Binding Protein is produced by our Mammalian expression system and the target gene encoding Ala26-Val481 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Lipopolysaccharide-Binding Protein is produced by our Mammalian expression system and the target gene encoding Ala26-Val481 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 52.0 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.2.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Lipopolysaccharide binding protein (LBP) is a plasma protein, belongs to a member of structurally and functionally related proteins which includes bactericidal permeability-increasing protein (BPI), plasma cholesteryl ester transfer protein (CETP) and phospholipid transfer protein (PLTP). It is involved in the acute-phase immunologic response to gram-negative bacterial infections. In cooperation with BPI. LBP binds LPS and interacts with the CD14 receptor, most likely playing a role in regulating LPS-dependent monocyte responses. Studies suggest that LBP is necessary for the rapid acute-phase response to LPS but not for the clearance of LPS from circulation. Finally, t The LBP gene is found on chromosome 20, directly downstream of the BPI gene.
Research Area: Microbiology, immunology
