Description
Recombinant Human Ketohexokinase/KHK Protein (His Tag) | PKSH032672 | Gentaur US, UK & Europe Disrtribition
Synonyms: Ketohexokinase; Hepatic fructokinase;KHK
Active Protein: N/A
Activity: Recombinant Human Ketohexokinase is produced by our Mammalian expression system and the target gene encoding Met1-Val298 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Ketohexokinase is produced by our Mammalian expression system and the target gene encoding Met1-Val298 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 33.7 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 50nM KCl, 10%Glycerol, pH7.4.
Reconstitution: Not Applicable
Background: Ketohexokinase, also known as Hepatic fructokinase, is a member of the carbohydrate kinase PfkB family. It exits as a homodimer and most abundant in liver, kidney, gut, spleen and pancreas. Low levels also found in adrenal, muscle, brain and eye.This enzyme catalyzes conversion of fructose to fructose-1-phosphate. It is the first enzyme with a specialized pathway that catabolizes dietary fructose. Defects in KHK are the cause of fructosuria.
Research Area: Signal Transduction, Cancer, metabolism,
