Description
Recombinant Human IPPI2/IDI2 Protein (His Tag) | PKSH032661 | Gentaur US, UK & Europe Disrtribition
Synonyms: Isopentenyl-Diphosphate Delta-Isomerase 2; Isopentenyl Pyrophosphate Isomerase 2; IPP Isomerase 2; IPPI2; IDI2
Active Protein: N/A
Activity: Recombinant Human Isopentenyl Pyrophosphate Isomerase 2 is produced by our E.coli expression system and the target gene encoding Met1-Val227 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human Isopentenyl Pyrophosphate Isomerase 2 is produced by our E.coli expression system and the target gene encoding Met1-Val227 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 28.9 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 1mM DTT, 0.1mM PMSF, pH 8.0.
Reconstitution: Not Applicable
Background: Isopentenyl Pyrophosphate Isomerase 2 (IDI2) belongs to the IPP isomerase type 1 family. Both isozymes, IDI1 and IDI2 are localized to the peroxisome by a PTS1-dependent pathway. IDI2 is expressed in skeletal muscle, which contains one nudix hydrolase domain. IDI2 binds one magnesium per subunit. IDI2 catalyzes the 1, 3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). It is reported that IDI2 is regulated independently from IDI1, by a mechanism that may involve PPAR-α.
Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,
