Recombinant Human INPP5A Protein (His Tag) | PKSH033170

Recombinant Human INPP5A Protein (His Tag) | PKSH033170 | Gentaur US, UK & Europe Disrtribition

Synonyms: Type I inositol 1;4;5-trisphosphate 5-phosphatase; INPP5A

Active Protein: N/A

Activity: Recombinant Human Type I Inositol-polyphosphate Phosphatase is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Type I Inositol-polyphosphate Phosphatase is produced by our Mammalian expression system and the target gene encoding Met1-Val410 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 48.5 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, pH7.4.

Reconstitution: Not Applicable

Background: Type I inositol 1, 4, 5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1, 4, 5-trisphosphate 5-phosphatase type I family. Type I inositol-1, 4, 5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1, 4, 5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation.

Research Area: Signal Transduction,