Recombinant Human IMPA2/IMPase 2 Protein (His Tag) | PKSH032591

Recombinant Human IMPA2/IMPase 2 Protein (His Tag) | PKSH032591 | Gentaur US, UK & Europe Disrtribition

Synonyms: Inositol Monophosphatase 2; IMP 2; IMPase 2; Inositol-1(or 4)-Monophosphatase 2; Myo-Inositol Monophosphatase A2; IMPA2; IMP.18P

Active Protein: N/A

Activity: Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Inositol Monophosphatase 2 is produced by our E.coli expression system and the target gene encoding Met1-Lys288 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 33.5 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 2mM DTT, pH 8.0.

Reconstitution: Not Applicable

Background: Inositol monophosphatase 2, also known as Inositol-1(or 4)-monophosphatase 2, Myo-inositol monophosphatase A2 and IMPA2, is an enzyme which belongs to the inositol monophosphatase family. IMPA2 catalyzes the dephosphoylration of inositol monophosphate with cofactor Magnesium and Inhibited by high Li+ and restricted Mg2+ concentrations. IMPA2 plays an important role in phosphatidylinositol signaling. IMPA2 can use the myo-inositol monophosphates, scylloinositol 1, 4-diphosphate, glucose-1-phosphate, beta-glycerophosphate, and 2'-AMP as substrates. IMPA2 is a pharmacological target for lithium Li(+) action in brain, it is considered to have a role in schizophrenia and bipolar disorder.

Research Area: Signal Transduction, Neuroscience, Cancer, metabolism,