Description
Recombinant Human IL2RG/CD132 Protein (aa 23-262, Fc Tag) | PKSH033410 | Gentaur US, UK & Europe Disrtribition
Synonyms: Cytokine receptor common subunit gamma; Interleukin-2 receptor subunit gamma; gammaC; P64; CD132; IL2RG; SCIDX;SCIDX1; CIDX
Active Protein: N/A
Activity: Recombinant Human Cytokine receptor common subunit gamma is produced by our Mammalian expression system and the target gene encoding Leu23-Ala262 is expressed with a Fc tag at the C-terminus.
Protein Construction: Recombinant Human Cytokine receptor common subunit gamma is produced by our Mammalian expression system and the target gene encoding Leu23-Ala262 is expressed with a Fc tag at the C-terminus.
Fusion Tag: C-Fc
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 55.4 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: IL2RG contains one fibronectin type-III domain. IL2RG is an important signaling component of many interleukin receptors; including those of interleukin -2; -4; -7 and -21; and is thus referred to as the common gamma chain. IL2RG interacts with SHB upon interleukin stimulation and HTLV-1 accessory protein p12I. Defects in IL2RG are the cause of X-linked combined immunodeficiency (XCID) and severe combined immunodeficiency X-linked T-cell-negative /B-cell-positive / NK-cell-negative (XSCID).
Research Area: Cancer, immunology
