Description
Recombinant Human IL-4 Protein | PKSH500030 | Gentaur US, UK & Europe Disrtribition
Synonyms: Interleukin-4, IL4, B-cell stimulatory factor 1, BSF-1, Binetrakin, Lymphocyte stimulatory factor 1, Pitrakinra
Active Protein: N/A
Activity: A DNA sequence encoding the Human IL4 protein (P05112) (His25-Ser153) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Human IL4 protein (P05112) (His25-Ser153) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 15 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% tween-80.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages. Stimulates autophagy in dendritic cells by interfering with mTORC1 signaling and through the induction of RUFY4.
Research Area: Cancer, Cardiovascular, Immunology, Cytokines
