Recombinant Human ICAM-2/CD102 Protein (His Tag) | PKSH033641

Recombinant Human ICAM-2/CD102 Protein (His Tag) | PKSH033641 | Gentaur US, UK & Europe Disrtribition

Synonyms: Intercellular Adhesion Molecule 2; ICAM-2; CD102; ICAM2

Active Protein: N/A

Activity: Recombinant Human ICAM-2 is produced by our Mammalian expression system and the target gene encoding Lys25-Gln223 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human ICAM-2 is produced by our Mammalian expression system and the target gene encoding Lys25-Gln223 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per μg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 23.13 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 2mM CaCl2, 2mM MgCl2, 5% Threhalose, pH 7.2.

Reconstitution: Please refer to the printed manual for detailed information.

Background: ICAM-2 is a 55-65 kD transmembrane glycoprotein possessing 2 extracellular Ig domains, a single transmembrane domain, and a short 26-amino acid cytoplasmic domain. ICAM-2 is expressed on most leukocytes, and is strongly expressed on vascular endothelial cells. Interactions of ICAM-2 and the integrin receptors mediate cell adhesion in a wide range of lymphocyte, monocyte, natural killer cell, and granulocytewith other cells, and play important roles in many adhesion-dependent immune and inflammation responses, such as T cell aggregation, NK-cell cytotoxicity and migration, lymphocyte recirculation, etc. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment.

Research Area: immunology, Stem cells