Recombinant Human HGPRT/HPRT1 Protein (His Tag) | PKSH032542

Recombinant Human HGPRT/HPRT1 Protein (His Tag) | PKSH032542 | Gentaur US, UK & Europe Disrtribition

Synonyms: Hypoxanthine-Guanine Phosphoribosyltransferase; HGPRT; HGPRTase; HPRT1; HPRT

Active Protein: N/A

Activity: Recombinant Human Hypoxanthine-Guanine Phosphoribosyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Ala218 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Hypoxanthine-Guanine Phosphoribosyltransferase is produced by our E.coli expression system and the target gene encoding Met1-Ala218 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 27.8 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 250mM NaCl, 2mM EDTA, 30% Glycerol, pH 8.0.

Reconstitution: Not Applicable

Background: Hypoxanthine-Guanine Phosphoribosyltransferase (HGPRT) has an important role in the generation of purine nucleotides through the purine salvage pathway. HPRT1 functions to salvage purines from degraded DNA to renewed purine synthesis, it acts as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.

Research Area: Cell biology, epigenetics and nuclear signal