Recombinant Human Hepcidin/HAMP Protein (GST Tag) | PKSH032540

Recombinant Human Hepcidin/HAMP Protein (GST Tag) | PKSH032540 | Gentaur US, UK & Europe Disrtribition

Synonyms: Liver-expressed antimicrobial peptide 1; Putative liver tumor regressor; HEPC; LEAP1

Active Protein: N/A

Activity: Recombinant Human Hepcidin is produced by our E.coli expression system and the target gene encoding Asp60-Thr84 is expressed with a GST tag at the N-terminus.

Protein Construction: Recombinant Human Hepcidin is produced by our E.coli expression system and the target gene encoding Asp60-Thr84 is expressed with a GST tag at the N-terminus.

Fusion Tag: N-GST

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 85 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 29.2 kDa

Formulation: Supplied as a 0.2 μm filtered solution of PBS, 50%glycerol, pH7.4.

Reconstitution: Not Applicable

Background: Hepcidin（HAMP）is a secreted protein that belongs to the hepcidin family.It is expressed in liver, heart and brain. It is involved in the maintenance of iron homeostasis, and it is necessary for the regulation of iron storage in macrophages, and for intestinal iron absorption. The preproprotein is post-translationally cleaved into mature peptides of 20, 22 and 25 amino acids, and these active peptides are rich in cysteines, which form intramolecular bonds that stabilize their beta sheet structures.

Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,