Recombinant Human H1F0/Histone H1 Protein (His Tag) | PKSH031355

Recombinant Human H1F0/Histone H1 Protein (His Tag) | PKSH031355 | Gentaur US, UK & Europe Disrtribition

Synonyms: CPN60;GROEL;H10;H1FV;HLD4;HSP60;HSP65;HSPD1;HuCHA60;SPG13

Active Protein: N/A

Activity: A DNA sequence encoding the human H1F0 (P07305) (Met 1-Lys 194) was expressed, with a polyhistide tag at the N-terminus.

Protein Construction: A DNA sequence encoding the human H1F0 (P07305) (Met 1-Lys 194) was expressed, with a polyhistide tag at the N-terminus.

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 92 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 22.4 kDa

Formulation: Lyophilized from sterile 50mM Tris, 600mM NaCl, 1mM DTT, pH 8.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: H1 histone family, member 0 (H1F0) is a member of the H1 histone family of nuclear proteins which are a component of chromatin in eukaryotic cells. It's involved in maintaining the structure of chromatin by packing the "beads on a string" sub-structure into a high order structure. The lysine-rich H1 histone family in mammals includes eleven members. In higher eukaryotes all H1 variants have the same general structure, consisting of a central conserved globular domain and less conserved N-terminal and C-terminal tails. These tails are moderately conserved among species, but differ among variants, suggesting a specific function for each H1 variant. Studies on the role of particular subtypes at specific developmental stages in lower eukaryotes, but also in vertebrates suggest that specific subtypes of H1 participate in particular systems of gene regulation. 

Research Area: epigenetics and nuclear signal