Recombinant Human GSTM2/GST4 Protein (His Tag) | PKSH030927

Recombinant Human GSTM2/GST4 Protein (His Tag) | PKSH030927 | Gentaur US, UK & Europe Disrtribition

Synonyms: GST4;GSTM;GSTM2-2;GTHMUS

Active Protein: N/A

Activity: A DNA sequence encoding the native human GSTM2 (P28161) (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus.

Protein Construction: A DNA sequence encoding the native human GSTM2 (P28161) (Met 1-Lys 218) was expressed, with a polyhistide tag at the N-terminus.

Fusion Tag: N-His

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 97 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 27.2 kDa

Formulation: Lyophilized from sterile 50mM Tris, 150mM NaCl, 10mM CaCl2, 0.05% Brig-35, pH 7.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: Glutathione S-transferase Mu 2, also known as GST class-mu 2, GSTM2-2 and GSTM2, is a cytoplasm protein which belongs to the GST superfamily and Mu family. GSTM2 / GST4 contains one GST C-terminal domain and one GST N-terminal domain. The glutathione S-transferases (GSTs) are a multigene family of enzymes largely involved in the detoxification of chemicals. Eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. Butyrate, an important luminal component produced from fermentation of dietary fibers, is an efficient inducer of GSTs and especially of GSTM2. Butyrate may act chemoprotectively by increasing detoxification capabilities in the colon mucosa.

Research Area: Signal Transduction, Tags & Cell Markers, Cancer, metabolism,