Description
Recombinant Human GSK3α Protein | PKSH500058 | Gentaur US, UK & Europe Disrtribition
Synonyms: Glycogen synthase kinase-3 alpha, GSK-3 alpha, Serine/threonine-protein kinase GSK3A, GSK3A
Active Protein: N/A
Activity: A DNA sequence encoding the Human GSK3α Protein (P49840)(97-448)was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the Human GSK3α Protein (P49840)(97-448)was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 80 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 39.4 kDa
Formulation: Lyophilized from sterile PBS, pH 7.4, 5% trehalose, 5% mannitol, 0.01% tween-80.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Constitutively active protein kinase that acts as a negative regulator in the hormonal control of glucose homeostasis, Wnt signaling and regulation of transcription factors and microtubules, by phosphorylating and inactivating glycogen synthase (GYS1 or GYS2), CTNNB1/beta-catenin, APC and AXIN1.
Research Area: Stem cells, Cardiovascular, Cell Biology, Neuroscience, Signal Transduction
