Description
Recombinant Human Growth Arrest-Specific Protein 7/GAS7 Protein (His Tag) | PKSH032510 | Gentaur US, UK & Europe Disrtribition
Synonyms: Growth Arrest-Specific Protein 7; GAS-7; GAS7; KIAA0394
Active Protein: N/A
Activity: Recombinant Human Growth Arrest-Specific Protein 7 is produced by our E.coli expression system and the target gene encoding Met1-Ile412 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human Growth Arrest-Specific Protein 7 is produced by our E.coli expression system and the target gene encoding Met1-Ile412 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 49.4 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 100mM NaCl, 2mM DTT, 10% Glycerol, pH 8.8.
Reconstitution: Not Applicable
Background: Growth Arrest-Specific Protein 7 (GAS7) is expressed primarily in terminalaly differentiated brain cells and predominantly in mature cerebellar Purkinje neurons. GAS7 may play a role in neuronal development by promoting maturation and morphological differentiation of cerebellar neurons. Inhibition of GAS7 production in terminally differentiating cultures of embryonic murine cerebullum impedes neurite outgrowth. The hyper-expression of GAS7 may play an major role in the initiation and development of huaman osteosarcoma.
Research Area: Cell biology, Cancer, epigenetics and nuclear signal
