Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag) | PKSH032505

Recombinant Human GPD1/GDP-C Protein (Human Cells, His Tag) | PKSH032505 | Gentaur US, UK & Europe Disrtribition

Synonyms: Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic; GPD-C; GPDH-C; GPD1; HTGTI

Active Protein: N/A

Activity: Recombinant Human Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic is produced by our Mammalian expression system and the target gene encoding Met1-Met349 is expressed with a 6His tag at the C-terminus.

Protein Construction: Recombinant Human Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic is produced by our Mammalian expression system and the target gene encoding Met1-Met349 is expressed with a 6His tag at the C-terminus.

Fusion Tag: C-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 38.6 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 10% Glycerol, pH 8.0.

Reconstitution: Not Applicable

Background: Glycerol-3-Phosphate Dehydrogenase [NAD(+)]; Cytoplasmic (GPDH-C) belongs to the NAD-Dependent Glycerol-3-Phosphate Dehydrogenase family. GPDH-C plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of Dihydroxyacetone Phosphate (DHAP) and reducing Nicotine Adenine Dinucleotide (NADH) to Glycerol-3-Phosphate (G3P) and NAD+. GPDH-C is inhibited by zinc ions and sulfate. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. GPDH-C is unlike Glyceraldehyde 3-Phosphate Dehydrogenase (GAPDH); they have different substrates.

Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,