Description
Recombinant Human GPD1/GDP-C Protein (E.coli, His Tag) | PKSH030541 | Gentaur US, UK & Europe Disrtribition
Synonyms: Glycerol-3-Phosphate Dehydrogenase [NAD(+)] Cytoplasmic; GPD-C; GPDH-C; GPD1; HTGTI
Active Protein: N/A
Activity: A DNA sequence encoding the human GPD1(P21695) (Met1-Met349) was expressed with a polyhistidine tag at the N-terminus.
Protein Construction: A DNA sequence encoding the human GPD1(P21695) (Met1-Met349) was expressed with a polyhistidine tag at the N-terminus.
Fusion Tag: N-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: Please contact us for more information.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 39.4 kDa
Formulation: Lyophilized from sterile 50mM Tris, 10% glycerol, pH 8.0
Reconstitution: Please refer to the printed manual for detailed information.
Background: GPD1; also known as glycerolphosphate dehydrogenase 1; is a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. GPD1 catalyzes the reversible redox conversion of dihydroxyacetone phosphate (DHAP); thus plays a critical role in carbohydrate and lipid metabolism. It also reduces nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. Meanwhile; GPD1 and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in GPD1 gene are a cause of transient infantile hypertriglyceridemia.
Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,
