Description
Recombinant Human GMPR Protein (Human Cells, His Tag) | PKSH033290 | Gentaur US, UK & Europe Disrtribition
Synonyms: GMP Reductase 1; Guanosine 5'-Monophosphate Oxidoreductase 1; Guanosine Monophosphate Reductase 1; GMPR; GMPR1
Active Protein: N/A
Activity: Recombinant Human GMP Reductase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Ser345 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human GMP Reductase 1 is produced by our Mammalian expression system and the target gene encoding Met1-Ser345 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 38.5 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris-HCl, 40% glycerol, 0.15M NaCl and 1mM DTT, pH8.0.
Reconstitution: Not Applicable
Background: GMP Reductase 1 (GMPR) is a member of the IMPDH/GMPR family. GMPR exists as a homotetramer and catalyzes the irreversible NADPH-dependent deamination of GMP to IMP. It functions in the conversion of nucleobase; nucleoside and nucleotide derivatives of G to A nucleotides; and in maintaining the intracellular balance of A and G nucleotides. GMP reductase gene expression may be regulated by MITF. At least two different alleles are known.
Research Area: Signal Transduction, Cell biology,
