Description
Recombinant Human GGPS1 Protein (His Tag) | PKSH032484 | Gentaur US, UK & Europe Disrtribition
Synonyms: Geranylgeranyl Pyrophosphate Synthase; GGPP Synthase; GGPPSase; (2E;6E)-Farnesyl Diphosphate Synthase; Dimethylallyltranstransferase; Farnesyl Diphosphate Synthase; Farnesyltranstransferase; Geranylgeranyl Diphosphate Synthase; Geranyltranstransferase; GGPS1
Active Protein: N/A
Activity: Recombinant Human Geranylgeranyl Pyrophosphate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Glu300 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human Geranylgeranyl Pyrophosphate Synthase is produced by our E.coli expression system and the target gene encoding Met1-Glu300 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 37.0 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, 20% Glycerol, pH 8.0 .
Reconstitution: Not Applicable
Background: Geranylgeranyl pyrophosphate synthase (GGPS1) is a member of the FPP/GGPP synthase family. GGPS1 is highly expressed in testis, heart and skeletal muscle. GGPS1 is localized in the cytoplasm and has geranylgeranyl diphosphate (GGPP) synthase activity. It catalyzes the trans-addition of the three molecules of IPP onto DMAPP to form geranylgeranyl pyrophosphate, an important precursor of carotenoids and geranylated proteins. Other transcriptional splice variants have been found.
Research Area: Cell biology, Cancer, metabolism