Description
Recombinant Human GGCT Protein (His Tag) | PKSH033273 | Gentaur US, UK & Europe Disrtribition
Synonyms: Gamma-Glutamylcyclotransferase; Cytochrome C-Releasing Factor 21; GGCT; C7orf24; CRF21
Active Protein: N/A
Activity: Recombinant Human gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus.
Protein Construction: Recombinant Human gamma-Glutamylcyclotransferase is produced by our E.coli expression system and the target gene encoding Met1-Leu188 is expressed with a 6His tag at the N-terminus.
Fusion Tag: N-6His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 23.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, pH 8.0.
Reconstitution: Not Applicable
Background: Human Υ-Glutamylcyclotransferase belongs to the Transferases family, specifically the Aminoacyltransferase. Gamma-Glutamylcyclotransferase catalyzes the formation of 5-Pxoproline from Gamma-Glutamyl Dipeptides. It plays an important role in Glutathione Homeostasis. Gamma-Glutamylcyclotransferase induces the release of Cytochrome C from the mitochondria resulting in the induction of apoptosis.
Research Area: Cell biology, Cancer, metabolism
