Description
Recombinant Human GALK1/Galactokinase Protein (His Tag) | PKSH033673 | Gentaur US, UK & Europe Disrtribition
Synonyms: Galactokinase; Galactose Kinase; GALK1; GALK
Active Protein: N/A
Activity: Recombinant Human GALK1 is produced by our E.coli expression system and the target gene encoding Met1-Leu392 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human GALK1 is produced by our E.coli expression system and the target gene encoding Met1-Leu392 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Human
Expressed Host: E.coli
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 85 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 43.3 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM TrisHCl, 150mM NaCl, pH 8.0.
Reconstitution: Not Applicable
Background: Galactokinase belongs to the GHMP kinase family and GalK subfamily. Galactokinase is more important to the galactose metabolism pathway. It modifies galactose to create a similar molecule called Galactose-1-Phosphate.Thus; a series of additional steps converts Galactose-1-Phosphate to another simple sugar Glucose; which is the main energy source for most cells. Galactokinase deficiency results in Galactosemia II; an autosomal recessive deficiency characterized by congenital cataracts during infancy and presenile cataracts in the adult population. The cataracts are secondary to accumulation of Galactitol in the lenses.
Research Area: Signal Transduction, Cell biology, Cancer, epigenetics and nuclear signal, metabolism,
