Recombinant Human Galectin-9/LGALS9 (N-GST) | PKSH033899

Recombinant Human Galectin-9/LGALS9 (N-GST) | PKSH033899 | Gentaur US, UK & Europe Disrtribition

Synonyms: Galectin-9; Gal-9; Ecalectin; Tumor antigen HOM-HD-21; LGALS9; Gal-9delta5

Active Protein: N/A

Activity: Recombinant Human Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus.

Protein Construction: Recombinant Human Galectin-9 is produced by our E.coli expression system and the target gene encoding Met1-Thr322 is expressed with a GST tag at the N-terminus.

Fusion Tag: N-GST

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.

Molecular Mass: 62.2 kDa

Formulation: Supplied as a 0.2 μm filtered solution of 1M PBS, 100 mM GSH, 15% Glycerol, pH 8.0.

Reconstitution: Not Applicable

Background: Galectin-9 is a cytoplasmic protein that contains two galectin domains. Galectin-9 is an S-type lectin that is over-expressed in Hodgkin's disease tissue. Galectin-9 binds galactosides and has high affinity for the Forssman pentasaccharide. Galectin-9 plays a role in thymocyte-epithelial interactions relevant to the biology of the thymus and Inhibits cell proliferation. Galectin-9 is a ligand for HAVCR2/TIM3 and induces T-helper type 1 lymphocyte (Th1) death. In addition, Galectin-9 suppresses tumor cell metastasis by interfering with the associations CD44, VCAM-1, Integrin α4β1

Research Area: N/A