Recombinant Human Galectin-7/LGALS7 Protein (GST Tag)(Active) | PKSH030935

Recombinant Human Galectin-7/LGALS7 Protein (GST Tag)(Active) | PKSH030935 | Gentaur US, UK & Europe Disrtribition

Synonyms: Galectin-7; Gal-7; HKL-14; PI7; p53-Induced Gene 1 Protein; LGALS7; PIG1; LGALS7B

Active Protein: Active protein

Activity: A DNA sequence encoding the human LGALS7 (P47929) (Ser 2-Phe 136) was fused with the GST tag at the N-terminus.

Protein Construction: A DNA sequence encoding the human LGALS7 (P47929) (Ser 2-Phe 136) was fused with the GST tag at the N-terminus.

Fusion Tag: N-GST

Species: Human

Expressed Host: E.coli

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 92 % as determined by reducing SDS-PAGE.

Endotoxin: Please contact us for more information.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 41.8 kDa

Formulation: Lyophilized from sterile PBS, pH 7.5

Reconstitution: Please refer to the printed manual for detailed information.

Background: LGALS7; also known as Galectin-7; is a member of the galectins family. The galectins are a family of beta-galactoside-binding proteins. There are at least 14 identified members in this family. Galectins share similarities in the CRD (the carbohydrate recognition domain). They are synthesized as cytosolic proteins. Though localized principally in the cytoplasm and lacking a classical signal peptide; galectins can also be stimulated to secretion by non-classical pathways or alternatively targeted to the nucleus. Galectins are implicated in modulating cell-cell and cell-matrix interactions. LGALS7 contains 1 galectin domain and is mainly expressed in stratified squamous epithelium. Galectin-7 could be involved in cell-cell and/or cell-matrix interactions necessary for normal growth control. LGALS7 is a pro-apoptotic protein that functions intracellularly upstream of JNK activation and cytochrome c release.

Research Area: Neuroscience, Cancer