Description
Recombinant Human G6PD Protein (His Tag) | PKSH032492 | Gentaur US, UK & Europe Disrtribition
Synonyms: Glucose-6-Phosphate 1-Dehydrogenase; G6PD
Active Protein: N/A
Activity: Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Glucose-6-Phosphate 1-Dehydrogenase is produced by our Mammalian expression system and the target gene encoding Ala2-Leu515 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 60.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of PBS, pH7.4.
Reconstitution: Not Applicable
Background: Glucose-6-Phosphate 1-Dehydrogenase (G6PD) is a cytosolic enzyme that belongs to the glucose-6-phosphate dehydrogenase family. G6PD participates in the pentose phosphate pathway that supplies reducing energy to cells by maintaining the level of the co-enzyme nicotinamide adenine dinucleotide phosphate (NADPH). G6PD produces pentose sugars for nucleic acid synthesis and main producer of NADPH reducing power. NADPH in turn maintains the level of glutathione in these cells that helps protect the red blood cells against oxidative damage. It is notable in humans that G6PD is remarkable for its genetic diversity. G6PD deficiency may cause neonatal jaundice, acute hemolysis, or severe chronic non-spherocytic hemolytic anemia.
Research Area: Signal Transduction, Cardiovascular, Cancer, metabolism,
