Description
Recombinant Human FGL1 Protein (His Tag)(Active) | PKSH033680 | Gentaur US, UK & Europe Disrtribition
Synonyms: Fibrinogen-like protein 1; FGL1; HP-041; Hepassocin; HFREP-1; LFIRE-1
Active Protein: Active protein
Activity: Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Fibrinogen-like Protein 1 is produced by our Mammalian expression system and the target gene encoding Leu23-Ile312 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 90 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per μg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 35 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris, 300mM NaCl, 10% Glycerol, 2mMEDTA, pH 8.0.
Reconstitution: Not Applicable
Background: Hepassocin; also known as hepatocyte-derived fibrinogen-related protein 1 (HFREP-1); is a liver-specific secreted protein belonging to the fibronogen superfamily; whose members share a fibrinogen domain at their C-termini. It is secreted by the liver and functions as a mitogen for hepatocytes. Hepassocin may play a role in the development of hepatocellular carcinomas. Hepassocin is a disulfide-linked homodimeric protein with a C-terminal fibrinogen domain. It is reported that it is a major immune inhibitory ligand of LAG-3.
Research Area: Cardiovascular
