Description
Recombinant Human FCRL1 Protein (His Tag) | PKSH033364 | Gentaur US, UK & Europe Disrtribition
Synonyms: Fc Receptor-Like Protein 1; FcR-Like Protein 1; FcRL1; Fc Receptor Homolog 1; FcRH1; IFGP Family Protein 1; hIFGP1; Immune Receptor Translocation-Associated Protein 5; CD307a; FCRL1; FCRH1; IFGP1; IRTA5
Active Protein: N/A
Activity: Recombinant Human Fc Receptor-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala17-Asn303 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human Fc Receptor-Like Protein 1 is produced by our Mammalian expression system and the target gene encoding Ala17-Asn303 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as lyophilized powder which is shipped with ice packs.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Molecular Mass: 32.2 kDa
Formulation: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
Reconstitution: Please refer to the printed manual for detailed information.
Background: Fc Receptor-Like Protein 1 (FCRL1) is a single-pass type I membrane protein that may function as an activating coreceptor in B cells. FCRL1 is primarily expressed in secondary lymphoid tissues by mature subsets of B cells. It can be detected in the spleen, lymph node, heart, skeletal muscle, kidney, liver and placenta. It is specifically expressed by mature B lineage cells with higher expression at the protein level in naive B cells compared to memory B cells. FCRL1 contains three extracellular C2-like immunoglobulin domains, a transmembrane domain, and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs and may play a role in the regulation of cancer cell growth.
Research Area: immunology
