Recombinant Human Fas Ligand / TNFSF6 (N-6His) | PKSH033886

Recombinant Human Fas Ligand / TNFSF6 (N-6His) | PKSH033886 | Gentaur US, UK & Europe Disrtribition

Synonyms: apoptosis (APO-1) antigen ligand 1; Apoptosis antigen ligand; APT1LG1CD95L; APTL; CD178 antigen; CD178; CD95L; CD95-L; Fas antigen ligand; Fas ligand (TNF superfamily, member 6); Fas Ligand; FASLCD95 ligand; FASLG; TNFSF6

Active Protein: N/A

Activity: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 6 is produced by our Mammalian expression system and the target gene encoding Pro134-Leu281 is expressed with a 6His tag at the N-terminus.

Protein Construction: Recombinant Human Tumor Necrosis Factor Ligand Superfamily Member 6 is produced by our Mammalian expression system and the target gene encoding Pro134-Leu281 is expressed with a 6His tag at the N-terminus.

Fusion Tag: N-6His

Species: Human

Expressed Host: Human Cells

Shipping: This product is provided as lyophilized powder which is shipped with ice packs.

Purity: > 95 % as determined by reducing SDS-PAGE.

Endotoxin: < 1.0 EU per µg as determined by the LAL method.

Stability and Storage: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Molecular Mass: 17.7 kDa

Formulation: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

Reconstitution: Please refer to the printed manual for detailed information.

Background: Fas ligand is also known as FasL, CD178, CD95L, or TNFSF6, is a homotrimeric type-II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. Its ability to induce apoptosis in target cells plays an important role in the development, homeostasis, and function of the immune system. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both.

Research Area: Cell biology, immunology, Stem cells