Description
Recombinant Human ERP44 Protein (His Tag) | PKSH032399 | Gentaur US, UK & Europe Disrtribition
Synonyms: Thioredoxin domain-containing protein 4; ER protein 44; KIAA0573; TXNDC4
Active Protein: N/A
Activity: Recombinant Human ER resident protein 44 is produced by our Mammalian expression system and the target gene encoding Glu30-Asp402 is expressed with a 6His tag at the C-terminus.
Protein Construction: Recombinant Human ER resident protein 44 is produced by our Mammalian expression system and the target gene encoding Glu30-Asp402 is expressed with a 6His tag at the C-terminus.
Fusion Tag: C-6His
Species: Human
Expressed Host: Human Cells
Shipping: This product is provided as liquid. It is shipped at frozen temperature with blue ice/gel packs. Upon receipt, store it immediately at<-20°C.
Purity: > 95 % as determined by reducing SDS-PAGE.
Endotoxin: < 1.0 EU per µg as determined by the LAL method.
Stability and Storage: Store at < -20°C, stable for 6 months. Please minimize freeze-thaw cycles.
Molecular Mass: 44.2 kDa
Formulation: Supplied as a 0.2 μm filtered solution of 20mM Tris HCl, 10% Glycerol, pH7.5.
Reconstitution: Not Applicable
Background: Endoplasmic reticulum resident protein 44 (TXNDC4) is is a 406 amino acid protein that contains one thioredoxin domain. TXNDC4 mediates thiol-dependent retention in the early secretory pathway and forms mixed disulfides with substrate proteins through its conserved CRFS motif.It can inhibit the calcium channel activity of ITPR1.It may have a role in the control of oxidative protein folding in the endoplasmic reticulum.
Research Area: Signal Transduction, Cell biology, metabolism,
